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Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking Kaletra and call your doctor at once if you have:

headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;
severe pain in your upper stomach spreading to your back, nausea and vomiting;
itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
high blood sugar (increased thirst, increased urination);
penis erection that is painful or lasts 4 hours or longer (if you take Kaletra with erectile dysfunction medication);
muscle weakness, tired feeling, joint or muscle pain, feeling short of breath; or
severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

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chest pain (especially when you breathe), dry cough, wheezing, feeling short of breath;
cold sores, sores on your genital or anal area;
rapid heart rate, feeling anxious or irritable, weakness or prickly feeling, problems with balance or eye movement;
trouble speaking or swallowing, severe lower back pain, loss of bladder or bowel control; or
swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence, loss of interest in sex.

Common side effects may include:

nausea, vomiting, diarrhea;
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changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

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